All the Facts: Oxafence Mask Spray
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Most masks just trap or shield pathogens. Infectious levels of SARS-CoV-2 virus can remain present on the outer layer of masks for seven days. Oxafence adds an active layer of protection that kills SARS-CoV-2 and Flu viruses on your mask all day while you are wearing it. It’s additional protection for those who need or want it most.
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Oxafence Active Protection Mask Spray is recommended for use on face masks. This product, however, does not change the “intended use” of the product on which it is applied. Do not reuse a mask intended for single-use. Not currently recommended for use on respirators, including P2/N95s/KN95s, unless specified by manufacturer.
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Store Oxafence Active Protection Mask Spray in a cool, dry, dark location when not in use. Product may cause discoloration to fabrics or surfaces. Apply Oxafence Active Protection Mask Spray with care to surrounding areas. Not intended to be swallowed or applied directly to skin. Do not use if hypersensitive to Methylene Blue. If pregnant, nursing, or taking medications with known interaction with ingredients, consult your physician prior to use. If an adverse reaction occurs, discontinue use and contact your physician while also notifying devices@health.govt.nz and info@OxafenceNZ.com.
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Oxafence Active Protection Mask Spray is WAND-listed and registered for sale in New Zealand as a Class IIb photocatalytic disinfectant surface coating [65345] intended to be applied to noninvasive soft surface devices to create a protective coating with an antimicrobial effect, that inactivates and decomposes harmful microorganisms through photodynamic action. This product, however, does not change the “intended use” of the product on which it is applied. Do not reuse a mask intended for single-use. Not currently recommended for use on respirators, including P2/N95s/KN95s, unless specified by manufacturer.
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Oxafence Mask Spray includes simple ingredients: water and special-grade Methylene Blue (a protective dye). Methylene Blue has been used as a textile dye since the 1870s and is considered an essential medicine by the World Health Organization. Methylene Blue has been commonly used for over one hundred years in treatment of disease, whether to mark skin or organs for surgeries, treat skin wounds, or as an injected or swallowed medication to treat poisonings or diseases such as malaria and methemoglobinemia. The amount of Methylene Blue used in Oxafence Mask Spray is far lower than the amount already medically approved for intravenous or oral uses. Other Oxafence products in development use other protective dyes, including Riboflavin (Vitamin B2), which is produced naturally and commonly consumed in food.
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Oxafence Mask Spray adds an active protective coating on masks. Methylene Blue, the protective dye in Oxafence Mask Spray, uses the power of visible light to enable the ongoing generation of singlet oxygen. Singlet oxygen is around us all the time, exists in our cells, and is naturally present in many commonly consumed products. Singlet oxygen is also well-known for its antimicrobial powers and ability to inactivate bacteria and viruses. Singlet oxygen kills SARS-CoV-2 and Influenza by disrupting their genomes, proteins, and outer shells. The singlet oxygen generated by Oxafence Mask Spray rapidly and naturally changes back to the very oxygen that we breathe every day. This mode of pathogen inactivation is often called Antimicrobial Photodynamic Inactivation (aPDI). A similar method, Photodynamic Therapy (PDT), has been deployed clinically since the 1980s for various treatments.
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The “Development of Methods for Mask and N95 Decontamination” (DeMaND) Study demonstrated the efficacy of protective dyes (i.e., Methylene Blue) in decontaminating SARS-CoV-2 and other viruses from masks. This study, and many other follow-on studies, were conducted by a multinational COVID-19 Task Force of 52 researchers and 13 institutions. The WHO DeMaND Study also demonstrated that PPE pre-treated with Methylene Blue provided ongoing inactivation of coronaviruses. Singletto, Inc. (the manufacturer of Oxafence Mask Spray) has continued to develop data supporting and expanding upon the DeMaND findings under the leadership of Dr Thomas Lendvay (pediatric surgeon), Dr James Chen (neurosurgeon), and Dr Christopher Mores (virologist). Singletto’s SARS-CoV-2 inactivation studies are performed by U.S.- and Canadian-based Biosafety Level 3 (BSL-3) University-affiliated laboratories. Influenza A/H1N1 inactivation studies are performed by an independent U.S. ISO-accredited laboratory. The Oxafence technology in Oxafence Mask Spray begins working immediately and, by 30 minutes, has inactivated 99.9% of SARS-CoV-2 and 95% of H1N1. Testing is conducted in the ambient light commonly present in laboratories and normal indoor settings (~500-700 lux). Oxafence technology provides residual protection, even at 24 hours.
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We'd love to hear from you. Please email us at Info@OxafenceNZ.com.
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Please contact your Henry Schein Territory Manager or visit the Henry Schein Webshop.